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Precision Radiotherapy for Pancreatic Cancer: MR-guided, Stereotactic Body Radiotherapy (SBRT), and Real-Time Tracking (Chinese Only)

Precision Radiotherapy for Pancreatic Cancer: MR-guided, Stereotactic Body Radiotherapy (SBRT), and Real-Time Tracking

    質子及光子放射治療愈趨精準,成功追蹤腫瘤的重大突破是先進定位及導航技術的革新,例如磁力共振導航放射治療(MR-guided Radiotherapy),可在每次治療中更清晰、精確地對準腫瘤位置,集中射線以進一步提升治療的準繩度及劑量,達到最有效的腫瘤控制。

     

    以胰臟癌為例,其位置位於腹部與盆腔深處,因此難以在早期階段發現,只有約15至20%患者適合接受根治性的手術,大部分患者也需要進行放療。惟受呼吸影響,腫瘤或附近器官的位置會有變化,因此傳統電療必須擴大靶區,避免靶點超出靶區而無法照射,確保足夠劑量。現時有一種電療方法——立體定位放射治療(Stereotactic Body Radiation Therapy,簡稱SBRT),在影像導航技術的協助下,以極高的精準度及更高劑量進行電療。

     

    胰臟癌電療縮短至 3-5 次

     

    劑量得以更精準照射在靶點,可令療程由傳統方式的25至30次,大幅縮短為3至5次,約於兩星期內完成,患者可盡快繼續其他治療,如藥物治療及免疫治療等,以更有效地消滅癌細胞。目前醫學研究已經證明,立體定位放射治療的效果,足以媲美手術割除腫瘤,存活率亦有所提升。

     

    除了成效,治療安全性也是關鍵。傳統上,胰臟癌放射治療的最大挑戰,是有機會令鄰近的十二指腸、胃部和小腸出現後遺症。現時新式的磁力共振放 射治療機器已配有追蹤腫瘤的技術(MotionManagement),可在治療期間同步追蹤腫瘤,當射線偏離軌道便會立刻停止。目前已有多項國際研究,將磁力共振電療納入胰腺癌治療中,其他研究亦顯示治療能將腸道副作用減少至10%或以下。多種新式治療方案均能兼顧高劑量與減輕副作用,對病人而言是個喜訊。

     

    撰文:養和質子治療中心主任、臨床腫瘤科專科醫生 張天怡醫生

     

    文章於2026年3月25日刊於《明報》「養和醫道百科」專欄

     

    About Dr. CHANG Tien Yee, Amy

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    Thumbnail of Dr. CHANG Tien Yee, Amy

    張天怡醫生

    Dr. CHANG Tien Yee, Amy

    HKSH Eastern Medical Centre

    Co-Director, Proton Therapy Centre

    Hong Kong Sanatorium & Hospital

    Honorary Consultant in Clinical Oncology

    Specialist in Clinical Oncology

    Honorary Clinical Assistant Professor, Department of Clinical Oncology (HKU)

    Clinical Associate Professor (Honorary), Department of Medicine and Therapeutics (CUHK)

    • MBBS (HK)
    • FRCR
    • FHKCR
    • PDipID (HK)
    • PDip Epidemiology and Biostatistics (CUHK)
    • FHKAM (Radiology)

    Contact Us

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    Happy Valley

    Address:
    3/F, Li Shu Fan Block,
    Hong Kong Sanatorium & Hospital,
    2 Village Road, Happy Valley, Hong Kong
    Service hours:
    Monday to Friday: 9:00 am - 5:00 pm
    Saturday: 9:00 am - 1:00 pm
    Closed on Sundays and Public Holidays
    Consultation by Appointment

    Tel.:
    (852) 2835 8877
    Email:
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    Fax:
    (852) 2892 7520
    WhatsApp:
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    Island East

    Address:
    11/F, HKSH Eastern Building,
    3 Tung Wong Road, Shau Kei Wan, Hong Kong
    Service hours:
    Monday to Friday: 9:00 am - 5:00 pm
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    Closed on Sundays and Public Holidays
    Consultation by Appointment

    Tel.:
    (852) 2917 1200
    Email:
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    Fax:
    (852) 2892 7599
    WhatsApp:
    (852) 2917 1200
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    Please provide name and contact number in text message in WhatsApp. Our Centre will contact you by phone to confirm. Do not send voice messages or graphics.
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    Island East

    Address:
    8/F, Tsao Yin Kai Block,
    3 A Kung Ngam Village Road, Shau Kei Wan, Hong Kong
    Service hours:
    Monday to Friday: 9:00 am - 5:00 pm
    Saturday: 9:00 am - 1:00 pm
    Closed on Sundays and Public Holidays
    Consultation by Appointment

    Tel.:
    (852) 2917 5080
    Email:
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    Fax:
    (852) 2892 7406
    WhatsApp:
    (852) 2917 5080
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    Please provide name and contact number in text message in WhatsApp. Our Centre will contact you by phone to confirm. Do not send voice messages or graphics.