The non-invasive Histotripsy utilises high-intensity focused ultrasound to precisely target liver tumours. This method creates microbubbles within the tumours that rapidly expand and collapse, generating shockwaves that disrupt and liquefy the tumours while causing minimal impact on surrounding tissues.

HKSH Cancer Center offers comprehensive and advanced treatment options for tackling liver cancer. If patient is not suitable for histotripsy, the experienced medical team will tailored alternative, effective and safe cancer treatment plan to meet individual needs.


Histotripsy Image






Treatment Assessment and Arrangement

The non-invasive histotripsy is an innovative treatment option, suitable for addressing both primary and metastatic liver cancer, for liver cancer patients who meet specific medical criteria, such as tumour size, location, etc. To help patients develop the most appropriate personalised treatment plan, HKSH's professional medical team provides a "Pre-Treatment Assessment" for patients diagnosed with liver cancer. Once it is confirmed that histotripsy is an appropriate treatment, the medical team will arrange it accordingly for the patient.  

Treatment package and service details


Pre-treatment Assessment Package

Package Price HK$ 8,000*


Managed by dedicated histotripsy doctor*
Ultrasound examination#
Physical investigation
(blood test, electrocardiogram, chest X-ray)

*If patient is unsuitable for treatment after doctor consultation, only the consultation fee in the sum of HK$2,000 will be charged.

# If the patient is assessed to be unsuitable following an ultrasound examination, both the consultation fee and the ultrasound examination fee in the sum of HK$5,000 will be charged.


Liver Cancer Histotripsy Package

Package Price HK$ 310,000

For Hong Kong Residents HK$260,000



Treatment charges
In-house doctor fees
Anaesthesia fee
General ward room charges
(2 Days 1 Night)
Equipment and instrument charges
Nursing care charges
Basic medication fee, consumables, and materials charges

Frequently Asked Questions:

Histotripsy is an innovative and non-invasive treatment for liver cancer. The technology utilises high-intensity focused ultrasound to targeted liver cancer tissues. The microbubbles created within the tumour would rapidly expand and collapse, generating shock waves that disrupt and liquefy the tumour. The treatment process is guided in real-time by advanced ultrasound imaging technology to ensure precise targeting of the tumour while minimising damage to surrounding healthy tissues.

Histotripsy is a non-invasive treatment that does not involve radiation, thermal energy, or incision. It significantly reduces side effects, and patients experience minimal pain and are left with no scars after the treatment.

In addition, the precise treatment minimises damages to the surrounding tissues. Patients typically recover faster after the treatment, helping them return to their daily routines more quickly.

Non-invasive Histotripsy is suitable for patients with primary or metastatic liver cancer. It may also be considered for patients who are not suitable for surgery, or those experienced failure in other liver cancer treatments. To undergo histotripsy, patients must meet specific medical criteria. Before treatment, it is recommended that patients consult HKSH's doctors for an assessment to determine whether they are suitable for Histotripsy. For enquiries or appointments, please contact the HKSH Cancer Centre Service Hotline at (852) 5213 6365.

HKSH is now using the latest Histotripsy 2.0 system. This technology was approved by the U.S. Food and Drug Administration (FDA) for liver cancer treatment in 2023, and was first introduced in Asia through Hong Kong.

Patient is required to undergo the "Pre-treatment Assessment" provided by HKSH, including a doctor's consultation, an ultrasound examination, and, if necessary, a physical examination based on the ultrasound results. If the assessment confirms that histotripsy is suitable for the patient, the treatment will then be arranged.

The "Pre-treatment Assessment Package" includes a professional assessment conducted by dedicated specialists from the Histotripsy medical team of HKSH. Patient preliminarily deemed suitable for Histotripsy treatment will undergo an ultrasound examination and physical examinations, including blood test, electrocardiogram, and chest X-ray.

The service is managed by dedicated doctors from HKSH's Histotripsy medical team. Please contact HKSH Cancer Center Service Hotline at (852) 5213 6365 to arrange an appointment.

The treatment is performed under general anesthesia. A small water tank integrated into the Histotripsy device will be placed on the patient's abdominal cavity during treatment. The high-intensity ultrasonic waves emitted through the water tank target the tumour inside the body, disrupting and liquefying the tumour cells.

Histotripsy treatment is non-invasive and leaves no wounds, resulting in minimal pain and a faster recovery. After the treatment, doctor will monitor the patient's condition, and most patients can typically be discharged the following day.

Histotripsy is a non-invasive treatment and no radiation or thermal energy is involved. As such, the patients usually would not feel uncomfortable. As the immune system will be activated to clear the fragmented tissue after the treatment, patients may experience mild flu-like symptoms. These can be managed with adequate rest, hydration, and sufficient nutrition intake. Some patients may also experience minimal pain.

HKSH Cancer Centre, equipped with state-of-art diagnostic and treatment equipment, can provide a wide range of treatment options, such as surgery, radiotherapy, and chemotherapy, to patients. Our experienced medical team will offer professional advice and recommend the most appropriate treatment plan tailored to patients' needs.

HKSH is using the latest Histotripsy 2.0 system. Our "Liver cancer Histotripsy Package" includes treatment charges, in-house doctor fees, anaesthesia fees, equipment and instrument charges, nursing care charges, basic medication fee, consumables and materials charges, and general ward room charges (2 days 1 night). Patient can also choose semi-private single room or private room with additional fee. Please contact us for details.

HKSH provides Histotripsy treatment in package price HK$310,000; and offers HK$260,000 package price for Hong Kong residents.

Aligned with our value of "Quality in Service, Excellence in Care", HKSH provides tailored patient services to overseas patients who seek physician consultations, second medical opinions, specialised surgical procedures, and a full range of comprehensive oncology treatments. The International Patient Services at HKSH is here to ensure personalised, seamless, and streamlined services for patients seeking treatment in HKSH. Each visiting patient is assigned a dedicated member of our medical concierge team, who offers personal assistance from the initial phone call to the post-treatment records delivery. We hope, by supporting every aspect of the patient journey, to enable our patients to focus on treatment and recovery. For more details, please click here to learn more. For making appointments, please contact the HKSH Cancer Center Service Hotline at (852) 5213 6365.

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